The Athlete's NAD Protocol

The Athlete's NAD Protocol

NAD+ levels decline by approximately 50% between ages 20 and 50. For athletes, this decline directly impacts energy production, recovery, and performance. While your training programme builds strength and endurance, optimising your NAD+ levels ensures your cells can actually deliver on that training.

This guide outlines the evidence-based NAD+ protocol that's helping athletes maintain peak performance, recover faster, and extend their competitive years.

Why Athletes Need More NAD+

NAD+ is the cellular fuel that powers energy production in your mitochondria. During intense training, your body's energy demands multiply exponentially, depleting NAD+ stores faster than they can be replenished naturally.

Without adequate NAD+, several performance-limiting factors occur:

  • ATP production becomes inefficient
  • Muscle fatigue sets in earlier
  • Recovery between sessions slows dramatically
  • Cellular repair mechanisms can't keep up with training damage

For athletes, maintaining optimal NAD+ levels isn't just beneficial—it's essential for consistent high-level performance. This is where NAD+ boosting supplements become crucial for serious athletes.

The Research: What Studies Show

Recent clinical trials have provided concrete evidence for NAD+ supplementation in athletic performance:

a magnifying glass

The Guangzhou Study

A six-week randomised, double-blind study of 48 amateur runners tested three different NMN dosages against placebo. Results showed dose-dependent improvements in:

  • Oxygen uptake efficiency
  • Power at ventilatory thresholds
  • Aerobic capacity markers

The study found that 600-1200mg daily dosages produced the most significant improvements, particularly in oxygen utilisation at the muscular level. This research demonstrates how NMN supplementation can supercharge aerobic capacity for endurance athletes.

Safety Profile

Clinical trials have consistently shown NMN to be safe for daily use at dosages up to 1200mg daily for extended periods, with no serious adverse effects reported.

The Athlete's NAD+ Protocol

Based on current research and athlete feedback, here's a comprehensive protocol for optimising NAD+ levels:

Training Level Age Range Daily Dosage Timing Key Benefits
Recreational 18-30 250-500mg Pre-training Enhanced energy, basic recovery
Competitive 18-30 500-600mg Split dosing Improved endurance, faster recovery
Elite/Professional 18-30 600-900mg Split dosing Maximum performance, optimal recovery
Masters Athletes 30-50 600-1000mg Split dosing Age-related decline mitigation
Senior Athletes 50+ 800-1200mg Split dosing Comprehensive cellular support

Dosing Strategy

Split Dosing Approach:

  • Take half your daily dose with breakfast
  • Take the remaining half 30-60 minutes before training
  • On rest days, take the second dose with lunch

For detailed guidance on dosing, see our comprehensive guide on how much NMN you should take.

Cycling Protocol: While continuous supplementation appears safe, some athletes prefer a cycling approach:

  • 8-12 weeks on, 2-4 weeks off
  • Monitor training response and adjust accordingly

Timing Optimisation

Pre-Training Window: Taking NMN 30-60 minutes before training may enhance acute performance benefits.

Post-Training Support: Consider additional support with complementary compounds like TMG and resveratrol for enhanced recovery.

Beyond Basic NMN: The Complete Stack

Advanced athletes often combine NMN with synergistic compounds:

Core Stack:

  • NMN: 600-1000mg daily (primary NAD+ precursor)
  • TMG: 500-1000mg daily (supports methylation pathways)
  • Resveratrol: 150-500mg daily (activates sirtuins, enhances NMN effects)

Recovery Enhancement:

  • CoQ10: 100-200mg daily (mitochondrial support)
  • Alpha Lipoic Acid: 300-600mg daily (antioxidant protection)

Monitoring Your Response

Track these key performance indicators:

Training Metrics:

  • Time to fatigue during steady-state efforts
  • Recovery heart rate between intervals
  • Perceived exertion at submaximal intensities

Recovery Markers:

  • Morning resting heart rate
  • Sleep quality scores
  • Muscle soreness duration

Performance Indicators:

  • Power output at ventilatory thresholds
  • Sustainable pace/power improvements
  • Training consistency (fewer missed sessions due to fatigue)

The Bottom Line

NAD+ supplementation represents a evidence-based approach to supporting athletic performance at the cellular level. The research shows particular promise for endurance athletes and those experiencing age-related performance decline.

Key takeaways:

  • Start with 500-600mg daily and assess response
  • Split dosing appears most effective
  • Effects are cumulative—benefits increase over 6-12 weeks
  • Combine with proper training, nutrition, and recovery protocols

Remember: NAD+ supplementation enhances your body's natural performance capabilities—it doesn't replace proper training, nutrition, or recovery. Think of it as premium fuel for your cellular engine, allowing you to get the most from every training session and competition.

Ready to Optimise Your Athletic Performance?

Whether you're just starting your NAD+ journey or looking to upgrade your current protocol, we've developed two research-backed options specifically for athletes.

Our Pure NMN Supplement provides 500mg of pharmaceutical-grade NMN per capsule—perfect for athletes who want complete control over their dosing strategy.

For those seeking maximum convenience and synergistic benefits, our NMN Complex combines NMN with TMG and resveratrol in scientifically-optimised ratios, eliminating the guesswork and providing comprehensive cellular support in a single supplement.

 Both products are manufactured to pharmaceutical standards and come with certificates of analysis, ensuring you get exactly what's on the label—nothing more, nothing less.


Always consult with a sports medicine professional before beginning any new supplement protocol, especially if you compete in tested sports where supplement regulations apply.

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