CoQ10 Supplements

Discover our premium CoQ10 supplement range designed to support heart health, cellular energy production, and overall vitality.

Coenzyme Q10 (CoQ10) is a naturally occurring nutrient and antioxidant found in cells throughout the body, playing an essential role in energy production and cardiovascular function. Our pharmaceutical-grade Co-Q10 formulations provide therapeutic doses to support your health, particularly if you're taking statins or concerned about heart health.

What Is Coenzyme Q10?

Coenzyme Q10, also known as ubiquinone in its oxidised form and ubiquinol in its reduced form, is a fat-soluble compound that acts as an essential enzyme cofactor in the mitochondrial electron transport chain. This is where your cells produce adenosine triphosphate (ATP) - the energy currency that powers every cellular function.

CoQ10 is found naturally in every mitochondrion throughout your body, with particularly high concentrations in organs with high energy demands like the heart and brain. However, levels of CoQ10 naturally decline with age, and certain medications - particularly statins - can further reduce CoQ10 levels in your body.

The role of Coenzyme Q10 extends beyond energy production. As a powerful antioxidant, CoQ10 helps protect cells from oxidative damage whilst supporting the normal function of the heart and cardiovascular system.

Why CoQ10 Supplementation Matters

Age-Related Decline

CoQ10 levels peak in your early 20s and decline steadily thereafter. By age 40, your body may produce 30% less CoQ10 than in youth, and by 80, levels may drop by 60% or more. This decline can affect energy production and cellular function throughout the body.

Statin Medications

If you're taking statins to manage cholesterol, you should know these medications block the same biochemical pathway your body uses to produce CoQ10. Research published in systematic reviews shows statin use can reduce CoQ10 levels by up to 40%, potentially contributing to statin-induced myopathy and statin-associated muscle symptoms.

The Mayo Clinic and Cleveland Clinic both acknowledge that CoQ10 supplementation may help address muscle pain and fatigue some people experience when taking statins. Healthcare professionals increasingly recommend CoQ10 dietary supplements for patients on statin therapy.

Heart Failure Support

Coenzyme Q10 has been extensively studied for its potential role in supporting heart health, particularly in those with heart failure. Research shows patients with congestive heart failure often have significantly reduced blood levels of CoQ10 compared to healthy individuals.

A systematic review and meta-analysis of randomized controlled trials found that the effect of Coenzyme Q10 supplementation in heart failure patients showed promising results. According to research cited by the National Cancer Institute and in their health professional version documentation, CoQ10 may help improve heart failure symptoms and support cardiovascular function.

Studies suggest CoQ10 may help support heart function and potentially reduce cardiovascular mortality in those with heart problems, though supplements are not regulated as medications and results vary individually.

Our CoQ10 Supplement Range

CoQ10 100mg + Vitamin B1

Our entry-level formula provides 100mg of high-quality Coenzyme Q10 per capsule alongside Vitamin B1 (thiamine), which contributes to normal heart function and energy-yielding metabolism.

Ideal for:

  • Those new to CoQ10 supplementation
  • Maintenance support for general wellness
  • Budget-conscious individuals seeking quality CoQ10
  • Supporting normal cardiovascular function

Best value option for daily CoQ10 support at an accessible price point.

Now £14.99 (Regular price £19.99)

Co-Q10 Supplement (300mg)

Our high-potency formula delivers 300mg of pharmaceutical-grade Coenzyme Q10 per capsule - one of the highest doses available in the UK market.

Ideal for:

  • Those taking statins who need higher CoQ10 doses
  • Individuals over 50 experiencing age-related CoQ10 decline
  • Anyone seeking therapeutic-level support for heart health
  • Those with higher energy demands

This concentrated dose provides three times the amount of CoQ10 found in standard supplements, offering comprehensive support for mitochondrial function and cardiovascular wellness.

Now £23.99 (Regular price £27.99)

NMN + CoQ10 Bundle

Combine the power of NMN (Nicotinamide Mononucleotide) with high-dose CoQ10 for comprehensive cellular energy support. This bundle pairs:

  • NMN 500mg - Boosts NAD+ levels for cellular energy and mitochondrial function
  • CoQ10 300mg - Supports the electron transport chain and heart health

Why combine these? Both nutrients work within your mitochondria but through different mechanisms. NMN elevates NAD+ to fuel cellular processes, whilst CoQ10 directly participates in ATP production. Together, they provide synergistic support for energy production, particularly beneficial for those over 40.

Bundle savings: £50.00 (Regular price £54.98)

Mitochondrial Health Bundle

Our most comprehensive approach to cellular energy, combining three key nutrients:

  • CoQ10 - Essential enzyme in energy production
  • Alpha Lipoic Acid - Universal antioxidant and metabolic support
  • Resveratrol - Supports mitochondrial biogenesis

This carefully formulated bundle addresses multiple aspects of mitochondrial function, providing a complete over-the-counter dietary supplement protocol for those serious about cellular health and longevity.

Bundle savings: £47.99 (Regular price £56.97) - Currently sold out

Understanding CoQ10: Ubiquinone vs Ubiquinol

Coenzyme Q10 exists in two forms:

Ubiquinone - The oxidised form of CoQ10, which your body converts to ubiquinol. This is the most common and stable form used in supplements, including ours. Research shows the bioavailability of Coenzyme Q10 as ubiquinone is excellent when taken with a meal containing fat.

Ubiquinol - The reduced, active antioxidant form. Whilst some claim superior absorption, systematic reviews suggest that healthy individuals efficiently convert ubiquinone to ubiquinol in the body. Ubiquinone supplements offer better stability and value.

Our formulations use pharmaceutical-grade ubiquinone, which is absorbed from the small intestine, particularly when consumed with dietary fat. The body then converts it to ubiquinol as needed, with enterohepatic recycling and redistribution from the liver helping maintain steady blood levels.

The Science Behind CoQ10

Energy Production

Coenzyme Q10 is an antioxidant that plays a dual role in cellular function. Within the mitochondrion, it serves as a critical component of the electron transport chain, shuttling electrons between enzyme complexes to drive the production of adenosine triphosphate (ATP).

Without adequate CoQ10, this process becomes less efficient, potentially affecting energy levels and cellular function throughout your body.

Cardiovascular Support

The heart is one of the most metabolically active organs, beating roughly 100,000 times daily. This requires enormous amounts of ATP, making adequate CoQ10 levels crucial to support heart health and normal cardiovascular function.

Research cited by the American Heart Association suggests CoQ10 may help support the heart, particularly in individuals with specific health concerns. The efficacy of Coenzyme Q10 in supporting cardiovascular wellness has been examined in numerous clinical trials.

Antioxidant Protection

Beyond energy production, CoQ10 functions as a lipid-soluble antioxidant, protecting cell membranes from oxidative damage. This is particularly important in the cardiovascular system, where oxidative stress can impact function over time.

CoQ10 helps regenerate other antioxidants like vitamin E, providing comprehensive cellular protection.

Who Should Consider Taking CoQ10 Supplements?

Statin Users

If you're taking statins (such as atorvastatin, simvastatin, or rosuvastatin), CoQ10 supplementation deserves serious consideration. Research shows statins significantly reduce CoQ10 production, and many people experience muscle pain and fatigue as a result.

Healthcare professionals increasingly recommend 100-300mg of CoQ10 daily for those on statin therapy. Some patients report improvement in statin-associated muscle symptoms after several weeks of CoQ10 supplementation.

Important: CoQ10 doesn't interfere with statin efficacy. However, if you take warfarin or other blood thinners, consult your healthcare provider before starting CoQ10, as it may affect medication effectiveness.

Those Over 40

Natural CoQ10 production declines significantly after age 40. Supplementing with 100-300mg daily may help maintain energy levels and support cardiovascular function as you age.

Individuals with Heart Concerns

If you have heart failure, congestive heart failure, or other heart problems, CoQ10 supplementation may offer support. Studies in patients with heart failure have shown CoQ10 may help improve symptoms and quality of life.

Always discuss supplementation with your healthcare provider if you have cardiovascular conditions. The Mayo Clinic notes that whilst CoQ10 is generally considered safe, it should complement, not replace, conventional medical treatment.

Those with High Energy Demands

Athletes, busy professionals, and anyone with demanding physical or mental schedules may benefit from CoQ10's role in cellular energy production.

Specific Conditions

Research has explored CoQ10's potential benefits in various conditions:

  • Patients with nephrotic syndrome - Some research suggests CoQ10 may help, particularly in steroid-resistant nephrotic syndrome
  • Human skin health - As an antioxidant, CoQ10 may help protect against oxidative damage
  • Neurological support - High concentrations in the brain suggest a protective role

How to Take CoQ10 for Best Results

Dosage Guidance

Maintenance: 100mg daily for general wellness and prevention

Therapeutic: 200-300mg daily for statin users, those over 50, or individuals with specific health concerns

Heart Support: 200-300mg daily, as used in many clinical trials for heart failure

Timing and Absorption

CoQ10 is fat-soluble, meaning it's best absorbed when taken with a meal containing dietary fat. Taking CoQ10 supplements with breakfast or lunch that includes healthy fats (like eggs, avocado, or fish and nuts) significantly improves absorption.

Research shows a second plasma peak occurs hours after ingestion due to enterohepatic recycling, helping maintain steady CoQ10 levels throughout the day.

Form Matters

Whilst available as both capsule and tablet, we use vegetarian capsules for optimal dissolution and absorption. Tablets may have lower bioavailability compared to capsules.

Consistency

CoQ10 builds up in tissues over time. Many people notice improvements in energy and well-being after 4-8 weeks of consistent use. For heart health support, research typically examines periods of 3-6 months.

Is CoQ10 Safe?

CoQ10 is safe to take for most people and is generally well-tolerated. It's been used in clinical research at doses up to 1,200mg daily with minimal side effects.

Possible Side Effects

Whilst rare, some people experience:

  • Mild digestive upset
  • Nausea
  • Headaches
  • Insomnia (if taken late in the day)

These effects are typically mild and resolve with continued use or dose adjustment.

Drug Interactions

Warfarin: CoQ10 may reduce warfarin's effectiveness due to its vitamin K-like structure. If you take warfarin, consult your doctor before starting CoQ10.

Statins: CoQ10 doesn't interfere with statin medications - in fact, it may help address their side effects.

Who Should Consult a Healthcare Provider

Talk to your doctor before taking CoQ10 supplements if you:

  • Take blood-thinning medications
  • Are pregnant or breastfeeding
  • Have scheduled surgery
  • Have any serious health conditions

Food Sources of CoQ10

Whilst supplementation provides therapeutic doses, CoQ10 is also found naturally in foods, particularly:

  • Organ meats (heart, liver, kidney) - Highest concentrations
  • Fatty fish (salmon, mackerel, sardines) - Good amounts
  • Fish and nuts - Moderate amounts
  • Meat and poultry - Modest amounts
  • Spinach and broccoli - Small amounts

However, even a diet rich in these foods provides only 3-10mg of CoQ10 daily - far below the amounts shown beneficial in research. This is why supplementation is necessary for therapeutic effects.

Why Choose Longevity Formulas CoQ10?

Pharmaceutical-Grade Quality

Our CoQ10 is manufactured to pharmaceutical standards in GMP-certified UK facilities, ensuring consistent potency and purity in every capsule.

High-Potency Formulations

We offer both 100mg and 300mg strengths, allowing you to choose the appropriate dose for your needs. Our 300mg capsule eliminates the need to take multiple tablets daily.

Enhanced Formulations

Our CoQ10 100mg includes Vitamin B1, which contributes to normal heart function and energy metabolism, providing complementary cardiovascular support.

Value-Focused Bundles

Our combination bundles offer the best value whilst providing comprehensive support for cellular energy and mitochondrial health.

Clean Formulations

  • No unnecessary fillers or additives
  • Vegetarian-friendly capsules
  • Free from common allergens
  • Third-party tested for purity

CoQ10 Deficiency: Signs and Solutions

Whilst Coenzyme Q10 deficiency is rare, certain situations can lead to reduced levels:

Signs of low CoQ10 may include:

  • Persistent fatigue and low energy
  • Muscle weakness or pain
  • Cognitive difficulties
  • Reduced exercise tolerance

Contributing factors:

  • Age over 40
  • Statin use
  • Certain genetic conditions
  • Inadequate dietary intake
  • Increased oxidative stress

If you suspect CoQ10 deficiency, supplementation with 100-300mg daily typically restores healthy levels within several weeks to months.

Frequently Asked Questions

What's the difference between your 100mg and 300mg formulas?

The 100mg + Vitamin B1 formula provides a moderate dose suitable for general wellness, prevention, and those new to CoQ10. The 300mg formula offers therapeutic-level support for statin users, those over 50, or anyone seeking comprehensive cardiovascular and energy support. Both use the same high-quality CoQ10, just at different strengths.

Can I take CoQ10 if I'm not on statins?

Absolutely. Whilst CoQ10 is particularly beneficial for statin users, anyone can benefit from supplementation, especially after age 40 when natural production declines. CoQ10 supports cellular energy production, cardiovascular health, and provides antioxidant protection regardless of medication use.

How long until I notice benefits?

Most people notice improvements in energy levels within 2-4 weeks of consistent use. For cardiovascular support, research typically examines periods of 3-6 months. CoQ10 accumulates in tissues over time, so benefits often increase with continued use.

Should I take ubiquinone or ubiquinol?

Both forms work effectively. Our supplements use ubiquinone, which your body efficiently converts to ubiquinol (the active form). Systematic reviews show that healthy individuals achieve excellent absorption with ubiquinone, particularly when taken with fat. Ubiquinone is also more stable and offers better value.

What dose of CoQ10 should I take?

For general wellness: 100mg daily. For statin users or those over 50: 200-300mg daily. For heart health support: 200-300mg daily. These doses align with amounts used in clinical research. Start with a lower dose and increase if needed.

Can I take CoQ10 with other supplements?

Yes. CoQ10 works synergistically with many nutrients. Our bundles combine CoQ10 with complementary compounds like NMN, Alpha Lipoic Acid, and Resveratrol for comprehensive cellular energy support. CoQ10 can safely be taken alongside most vitamins and minerals.

Are there any side effects?

CoQ10 is generally well-tolerated. Possible side effects are rare and typically mild, including digestive upset or nausea. Taking CoQ10 with food usually prevents these issues. Avoid taking it late in the day if you experience sleep disturbances.

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Ready to support your cellular energy and heart health? Explore our CoQ10 supplement range and discover the difference pharmaceutical-grade Coenzyme Q10 can make.

These statements have not been evaluated by the Medicines and Healthcare products Regulatory Agency (MHRA). These products are not intended to diagnose, treat, cure or prevent any disease. Always consult with a healthcare professional before starting any new dietary supplement, particularly if you have existing health conditions or take medications.