Epigenetics—the study of how behaviours, nutrition, and environment influence the way your genes are expressed—has transformed our understanding of ageing. While your DNA sequence stays the same throughout life, epigenetic changes can turn genes “on” or “off,” shaping your health, vitality, and longevity trajectory.
At Longevity Formulas, we create premium, science-based epigenetic supplements designed to support healthy gene expression as part of a comprehensive longevity and healthspan strategy.
Understanding Epigenetics & Healthy Ageing
Think of your genome as a vast library of books. Epigenetic mechanisms determine:
- Which books (genes) are open and being read
- Which remain closed and silent
These regulatory processes—such as DNA methylation, histone modifications, and transcription factor activity—are influenced by lifestyle, environment, and targeted nutritional support.
The Epigenetic Clock & Biological Ageing
Research shows that epigenetic markers shift in predictable ways as we age, forming what’s known as the epigenetic clock—one of the most accurate biomarkers of biological ageing.
Supporting healthy epigenetic patterns may help:
- Promote youthful gene expression
- Improve cellular resilience
- Extend healthspan
Our Premium Epigenetic Support Supplements
Below is our curated collection of supplements formulated to support healthy gene regulation, NAD+ metabolism, sirtuin function, methylation, and cellular resilience.
NMN Supplement (Nicotinamide Mononucleotide)
How NMN Supports Epigenetic Health
- Boosts NAD+ levels, essential for sirtuin activity
- Enhances sirtuin function, key regulators of histone modifications
- Supports mitochondrial health, influencing nuclear gene expression
- Promotes cellular repair and resilience
Key Features:
500mg per capsule • Pharmaceutical-grade purity • UK-manufactured
NMN Complex
A Synergistic Multi-Pathway Epigenetic Formula
Combines complementary longevity ingredients for enhanced gene-expression support:
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NMN → NAD+ production & sirtuin activation
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Resveratrol → Activates SIRT1, a master epigenetic regulator
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TMG (Trimethylglycine) → Supports methylation pathways
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Additional cofactors for complete epigenetic wellness
Key Features:
Synergistic formulation • Enhanced bioavailability • UK-manufactured
Resveratrol
Epigenetic Benefits of Resveratrol
- Activates SIRT1, promoting youthful histone acetylation patterns
- Supports healthy inflammatory balance
- Enhances metabolic and mitochondrial health
- Strengthens cellular stress resistance
Key Features:
High potency • Superior absorption • UK-manufactured
Vitamin D3 + K2
How D3/K2 Supports Gene Expression
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Vitamin D functions as a transcription factor, influencing hundreds of genes
- Supports immune system epigenetic balance
- K2 promotes calcium regulation and systemic health
- Contributes to overall cellular resilience
Key Features:
Optimised D3/K2 ratio • Enhanced absorption • UK-manufactured
Alpha Lipoic Acid (ALA)
Epigenetic Actions of Alpha Lipoic Acid
- Helps maintain redox balance, essential for epigenetic enzyme activity
- Supports mitochondrial performance
- Promotes cellular detoxification pathways
- Enhances other antioxidant systems for broad protection
Key Features:
600mg per capsule • R-ALA for maximum bioactivity • UK-manufactured
The Science Behind Epigenetic Support
Key Mechanisms Influenced by Nutrition
Sirtuin Activation
NAD+-dependent sirtuins regulate histone acetylation and gene expression.
NMN and resveratrol are two of the most studied compounds supporting sirtuin pathways.
Healthy Methylation
DNA and histone methylation require optimal methyl donors.
TMG in our NMN Complex helps maintain balanced methylation patterns.
Histone Modification
Bioactives like resveratrol influence histone acetylation, potentially supporting youthful gene regulation.
Transcription Factor Regulation
Vitamin D directly influences gene expression by binding to DNA regulatory regions, impacting immunity, bone health, and cellular resilience.
Why Choose Longevity Formulas for Epigenetic Supplements?
Science-Driven Formulations
Evidence-based dosages, clinically relevant ingredients, and formulations guided by the latest longevity research.
UK Manufacturing Excellence
All products are manufactured in the UK under strict quality control standards to ensure exceptional purity and potency.
Premium Quality Guarantee
- No artificial fillers or additives
- Rigorous purity testing
- GMP-certified facilities
- Scientifically validated ingredients
Expert Guidance
Our team includes specialists in ageing and healthspan research who understand the central role of epigenetics in lifelong wellness.
How to Incorporate Epigenetic Support Into Your Routine
To maximise benefits:
- Supplement daily with targeted epigenetic nutrients
- Combine synergistic compounds such as NMN + Resveratrol
- Follow a nutrient-dense, plant-rich diet
- Maintain regular physical activity
- Prioritise sleep and stress reduction
These lifestyle factors reinforce healthy gene-expression patterns.
Begin Your Epigenetic Health Journey
Supporting your epigenetic health is one of the most advanced approaches to optimising longevity.
Our UK-made supplements provide targeted nutritional support for maintaining youthful gene expression, cellular resilience, and long-term vitality.
Explore the Epigenetic Health Collection and take charge of your biological ageing today.
Frequently Asked Questions About Epigenetic Supplements
Can supplements really influence epigenetics?
Yes. While supplements don’t change your DNA, research shows that certain nutrients can support the regulatory systems that influence gene expression.
How does epigenetic health relate to ageing?
Epigenetic drift is one of the hallmarks of ageing. Maintaining balanced epigenetic patterns may help preserve youthful cellular function and healthspan.
How long before I notice effects?
Some people report improved energy and mental clarity within weeks, but the most profound epigenetic benefits occur gradually with consistent long-term use.
Do lifestyle factors affect epigenetics?
Absolutely. Diet, exercise, sleep, and stress all influence epigenetic patterns and work synergistically with targeted nutrition.
How do these supplements differ from typical anti-ageing products?
Rather than treating symptoms, our supplements target the epigenetic regulation underlying many ageing processes—supporting health at the deepest cellular level.
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