NMN checker
Can you take NMN with creatine, coffee, statins or the pill? Search or browse 58 answers below. Each one gives a plain verdict, what is actually known, and how to fit them together. No human trial has tested NMN with any prescription medicine, so those answers tell you who to ask.
Vitamins, minerals and other supplements people take alongside NMN.
Yes. No study has reported a problem with taking NMN and creatine together, and they share no ingredients. A common routine is 3 to 5g of creatine a day with one 500mg Pure NMN capsule.
How to take them: Same time is fine. You don't need to space them apart.
Yes. No interaction has been reported between NMN and CoQ10. CoQ10 is fat-soluble, so it is usually taken with a meal that contains some fat.
How to take them: CoQ10 with a meal. NMN at the same meal or any other time.
Yes. No interaction has been reported, and you can take them at the same time. Marine collagen is made from fish, so it is not suitable if you have a fish allergy.
How to take them: Our Marine Collagen is a 10g scoop of powder. Mix it into a drink and take your NMN capsule alongside.
Yes, they are often taken together, but no trial shows NMN needs TMG. NMN Complex already contains 600mg TMG in each daily serving of 3 capsules.
How to take them: Taking NMN Complex? Don't add a separate TMG supplement. Taking Pure NMN? TMG can go alongside it.
Yes. No interaction has been reported. NMN Complex already contains 120mg trans-resveratrol in each daily serving.
How to take them: Taking NMN Complex? Don't add a separate resveratrol. Taking Pure NMN? A resveratrol capsule can go alongside it.
No study has tested NMN with pterostilbene, and no problem has been reported. NMN Complex already contains 120mg pterostilbene in each daily serving.
How to take them: Taking NMN Complex? Don't add separate pterostilbene.
No study has tested NMN with quercetin, and no problem has been reported. NMN Complex already contains 300mg quercetin in each daily serving.
How to take them: Taking NMN Complex? Don't add separate quercetin.
Yes. No interaction has been reported. The NHS says 400mg or less of magnesium a day from supplements is unlikely to cause harm. Our Magnesium Complex gives 375mg in 3 capsules, so count any magnesium in a multivitamin too.
How to take them: Magnesium with a meal. NMN at any time.
Yes. No interaction has been reported. The NHS says not to take more than 100 micrograms (4,000 IU) of vitamin D a day. Our D3 and K2 gives 75 micrograms of D3 and 100 micrograms of K2, so check a multivitamin doesn't take you over the limit.
How to take them: With a meal. If you take warfarin, vitamin K affects how it works, so speak to your anticoagulant clinic before taking any K2.
Yes. No interaction has been reported. NMN Complex contains 150 micrograms (0.15mg) of B12 a day. The NHS says 2mg or less of B12 a day from supplements is unlikely to cause harm.
How to take them: Add up B12 from the Complex, any B complex and any multivitamin.
Yes. NMN is not a vitamin and doesn't appear in multivitamins. Check the label for vitamin D, B12, niacin and magnesium so you don't double up with other supplements you take.
How to take them: Any time. A multivitamin is usually taken with breakfast.
No study has tested NMN with vitamin C, and no problem has been reported. The NHS says taking less than 1,000mg of vitamin C a day from supplements is unlikely to cause harm.
How to take them: Same time is fine.
No study has tested NMN with zinc, and no problem has been reported. The NHS says 25mg or less of zinc a day from supplements is unlikely to cause harm.
How to take them: Zinc can upset an empty stomach, so many people take it with food.
NMN is not an authorised form of niacin in Great Britain, so it isn't counted as niacin on a label. No interaction has been reported. The NHS says 17mg or less of nicotinic acid, or 500mg or less of nicotinamide, a day from supplements is unlikely to cause harm.
How to take them: Check how much niacin your multivitamin already gives you.
No study has tested NMN with fish oil, and no problem has been reported. Fish oil is not suitable if you have a fish allergy. If you take a blood thinner, tell your clinic about any fish oil you take.
How to take them: Fish oil with a meal. NMN at any time.
No study has tested NMN with krill oil, and no problem has been reported. Krill is a shellfish, so krill oil is not suitable if you have a shellfish allergy. If you take a blood thinner, tell your clinic.
How to take them: Krill oil with a meal. NMN at any time.
No study has tested NMN with NAC, and no problem has been reported. Our NAC is a 600mg capsule, taken once or twice a day.
How to take them: NAC between meals. NMN at any time.
No study has tested NMN with alpha lipoic acid, and no problem has been reported. Our ALA is a 300mg capsule. If you take any prescription medicine, ask a pharmacist before adding it.
How to take them: Same day is fine. Follow the ALA label for timing.
NR and NMN are closely related compounds, sold for the same reason. No study has tested taking both, and taking both doubles what you spend.
How to take them: Choose one. Our comparison sets out the differences.
NAD+ capsules, sublingual NAD+, NAD+ drips and NMN are sold for the same reason. No study has tested taking NAD+ products alongside NMN.
How to take them: Most people choose one. Our comparison sets out the differences in form, dose and cost.
Pure NMN and NMN Complex each give 500mg NMN a day. Taking both, or two NMN brands, doubles your NMN to 1,000mg a day, which is more than either label says.
How to take them: Pick one product and follow its label.
No interaction with NMN has been reported. The NHS warns that St John's wort interferes with many prescription medicines, including warfarin, the contraceptive pill and antidepressants.
How to take them: If you take any prescription medicine, don't take St John's wort without speaking to your GP.
No study has tested NMN with turmeric, and no problem has been reported. If you take warfarin or another blood thinner, ask your clinic before starting turmeric.
How to take them: Same time is fine.
No study has tested NMN with berberine, and no problem has been reported. If you take any prescription medicine, ask a pharmacist before adding it.
How to take them: Start one new supplement at a time, so you know how each one suits you.
No study has tested NMN with spermidine, and no problem has been reported. Some spermidine supplements are made from wheat germ, so check the label if you avoid gluten.
How to take them: Start one new supplement at a time, so you know how each one suits you.
No study has tested NMN with fisetin, and no problem has been reported. If you take any prescription medicine, ask a pharmacist before adding it.
How to take them: Start one new supplement at a time, so you know how each one suits you.
No study has tested NMN with ashwagandha, and no problem has been reported. If you take any prescription medicine, ask a pharmacist before adding it.
How to take them: Start one new supplement at a time, so you know how each one suits you.
Yes. Protein powder is a food, and no interaction with NMN has been reported.
How to take them: Same time is fine. Swallow the capsule with the shake.
No interaction with NMN has been reported. In the UK, melatonin is a prescription medicine.
How to take them: Tell the doctor who prescribed it that you take NMN.
No published human trial has tested NMN alongside any prescription medicine. These answers say what is known and who to ask.
No human trial has tested NMN with levothyroxine. The NHS says to take levothyroxine on an empty stomach, 30 to 60 minutes before food or caffeine, and that some supplements such as calcium and iron can stop it working properly.
How to take them: Keep levothyroxine on its own first thing. Take NMN later, for example with lunch, and ask your pharmacist about spacing.
No human trial has tested NMN with warfarin. The NHS says not to take St John's wort or vitamin K supplements with warfarin without speaking to your clinic. Pure NMN and NMN Complex contain no vitamin K. NMN Complex contains resveratrol, pterostilbene and quercetin.
How to take them: Speak to your anticoagulant clinic before starting, and give them the full ingredient list.
No human trial has tested NMN with apixaban, rivaroxaban or similar blood thinners. The NHS names St John's wort as a supplement to avoid with apixaban.
How to take them: Tell your GP or pharmacist before you start, and show them the label.
No human trial has tested NMN with aspirin or clopidogrel.
How to take them: Ask your pharmacist before starting, and give them the full ingredient list, especially for NMN Complex.
No human trial has tested NMN with statins. One NMN trial of 90 adults (NCT04823260) excluded people taking statins. NMN is a different compound from the nicotinic acid used in niacin and statin studies, so their results don't transfer to it.
How to take them: Tell your GP before you start.
No human trial has tested NMN with amlodipine or other blood pressure medicines.
How to take them: Tell your GP, and keep up any home blood pressure checks you already do.
No human trial has tested NMN with metformin or other diabetes medicines.
How to take them: Tell your GP or pharmacist, and keep up your usual blood sugar checks.
No human trial has tested NMN with Mounjaro, Wegovy or other GLP-1 medicines.
How to take them: Tell the prescriber or pharmacist who supplies your injections before starting any supplement.
No human trial has tested NMN with sertraline or other antidepressants.
How to take them: Ask your pharmacist before starting. Never change or stop an antidepressant without your GP.
No human trial has tested NMN with HRT.
How to take them: Tell your GP or menopause clinic before you start.
No human trial has tested NMN with the contraceptive pill. The NHS warns that St John's wort can stop the pill working.
How to take them: Ask your pharmacist if you are unsure.
No human trial has tested NMN with antibiotics. Some antibiotics shouldn't be taken at the same time as minerals such as calcium, iron, magnesium or zinc.
How to take them: Ask the pharmacist who gives you the antibiotic about any supplements you take.
No human trial has tested NMN with paracetamol or ibuprofen, and no problem has been reported.
How to take them: Follow the painkiller label. Ask a pharmacist if you take painkillers every day.
NMN has not been studied in people having cancer treatment.
How to take them: Speak to your cancer team before taking NMN or any other supplement.
Meals, coffee, alcohol and fasting.
Yes, either. NMN can be taken with or without food.
How to take them: Pick a time you will remember every day, such as with breakfast.
Yes. No interaction between NMN and coffee has been reported, and many people take their capsule with a morning coffee.
How to take them: If you also take levothyroxine, that medicine needs a gap before coffee. NMN doesn't.
No interaction between NMN and alcohol has been reported. The NHS advises no more than 14 units of alcohol a week, spread over 3 or more days.
How to take them: Take NMN at your usual time.
Yes. NMN can be taken without food. A capsule weighs less than a gram, so whether it counts as breaking your fast depends on how strict your fast is.
How to take them: Take it in your eating window if you want a strict fast.
No interaction between NMN and grapefruit has been reported. Grapefruit does affect some prescription medicines, so check your medicine leaflet.
How to take them: Same time is fine.
NMN Complex uses delayed-release HPMC capsules, so swallow them whole rather than opening them.
How to take them: Swallow capsules whole with water. Our comparison of capsules, powder and sublingual NMN explains the formats.
Pregnancy, surgery, exercise and other times people ask about.
NMN has not been studied in pregnancy. Don't take it while pregnant unless your doctor or midwife says otherwise.
How to take them: Speak to your GP or midwife about any supplement.
NMN has not been studied in breastfeeding.
How to take them: Speak to your GP or health visitor before taking it.
NMN has not been studied in full human trials in people trying to conceive. Our advice is not to take it while you are trying for a baby.
How to take them: Speak to your GP or fertility clinic.
No study has looked at NMN around surgery. Hospitals ask you to list every supplement you take before an operation, and may ask you to stop some beforehand.
How to take them: Tell your surgical team you take NMN and follow what they say.
Yes. Timing around exercise doesn't matter for NMN. Take it at the same time each day.
How to take them: Many people take it with breakfast, then creatine with a post-workout shake.
No. Human trials of NMN have only included adults, and our products are sold for adults.
How to take them: Not for children or teenagers.
Most NMN trials recruited healthy adults or people with one specific condition.
How to take them: Speak to your GP before starting if you have a long-term condition or see a specialist.
No study has looked at NMN and blood test results.
How to take them: Tell whoever orders the test that you take NMN, and follow any fasting instructions they give.
Human trials gave NMN every day, at 250 to 2,000mg, for up to about 24 weeks. A 2026 review of 10 trials found side effects were no more common than with a placebo. No trial has run for longer than about 6 months.
How to take them: Pure NMN is one 500mg capsule a day. Don't take more than the label says.
Not on the list?
We haven't covered that one yet. Ask us and we'll add it, or ask a pharmacist, who can check it against anything you take.
Example day
An example of how the timings above fit into one day. Only take what you need, and follow your own medicine instructions first.
Prescription medicines that need an empty stomach
For example levothyroxine, 30 to 60 minutes before food or coffee.
NMN, creatine, collagen
NMN works with or without food, so breakfast is an easy time to remember it.
CoQ10, vitamin D3 and K2, krill or fish oil, magnesium
These are usually taken with food, and the oils with a meal that has some fat.
NAC
NAC is usually taken away from food, once or twice a day.
Our NMN
NMN is classed as a novel food in Great Britain, and an application is being assessed by the Food Standards Agency. Our products are food supplements, not medicines. This page is general information, not medical advice. If you have a health condition, are pregnant or take medication, speak to your GP or pharmacist before taking any supplement.
No combination has been reported to cause harm, but three things are not worth doubling up on: NR, NAD+ supplements and a second NMN product, because they are sold for the same reason. Don't take NMN while pregnant, trying to conceive or under 18. If you take prescription medicine, avoid St John's wort, which the NHS says interferes with many medicines.
No published human trial has tested NMN alongside any prescription medicine, so nobody can tell you it is proven safe with yours. Show the label to your GP or pharmacist before you start. Our guide to NMN and common medications covers levothyroxine, warfarin, statins, metformin and more.
Yes, NMN is commonly taken with creatine, CoQ10, collagen, magnesium and vitamin D. No interaction has been reported with any of them. Check for overlap if you take NMN Complex, which already contains TMG, resveratrol, pterostilbene, quercetin and vitamin B12.
NMN can be taken with or without food. Choose a time you will remember every day. Our guide to when to take NMN covers morning and evening.
Add one new supplement at a time and keep everything else the same for a couple of weeks, so you know how each one suits you. Two daily slots, such as breakfast and your main meal, are easier to stick to than five.
Each answer is based on published human trials, NHS medicine and supplement guidance, and the labels of our own products. Nothing on this page is medical advice. A pharmacist can check NMN against everything you take, for free, without an appointment.
